The 42nd annual meeting of the Association for Chemoreception Sciences
April 29, 2020
Session: “Cell Types in Taste Buds And Tentacles” (Organizers: Thomas Finger and Sue Cinnamon)
Talk title: Salt-Responsive Cells - A Unique Cell Type?
Speaker: Akiyuki Taruno
Akiyuki Taruno chosen as one of the 2021 recipients of The Young Scientists' Award: The commendation for Science and Technology by the Minister of Education, Culture, Sports, and Technology - Japan.
April 6, 2021
Yu Yamada joined the lab
April 1, 2021
We report post-translational regulation of the CALHM1/3 channel by N-glycosylation and S-palmitoylation, providing insights into the fine control of associated physiological processes including gustation.
March 31, 2021
Okui, Murakami et al. FASEB Journal 2021
Akiyuki Taruno chosen as one of JST FOREST researchers
Feb 2, 2021
Fusion Oriented Research for disruptive Science and Technology
Kengo Nomura chosen as one of JST ACT-X researchers
October 20, 2020
Our review paper on taste transduction and channel synapses is out.
September 17, 2020
Taruno et al. Pflügers Archiv - European Journal of Physiology - 2020
To transmit taste information from taste bud cells to afferent neurons, all taste qualities excluding sour employ the unique "channel synapses" which involves CALHM1/3 channels for neurotransmitter release instead of synaptic vesicles. This review summarizes the current view of taste transduction and neurotransmission with emphasis on our recent discoveries on channel synapses and salty taste.
The fantastic virtual ISOT2020
August 5, 2020
Session: “In bad taste: Sensors and Circuits for Bitter, Salty, and Sour” moderated by Emily Liman and Craig Montell
Talk title: All-electrical Signal Transduction and "Channel Synapses" Mediate Sodium Taste
Speaker: Akiyuki Taruno
We report the structures of CALHM channels (killifish CALHM1, human CALHM2 and C.elegans CLHM-1). The findings provide insights into the structure and ATP permeation of the neurotransmitter-release channel in taste cells. A wonderful collaboration with Nureki Lab (Tokyo U.)
July 17, 2020
Demura et al. Science Advances 2020
Our paper on salty taste is out.We report the identity of taste cells dedicated to the sodium-selective, attractive component of salty taste (aka sodium cells) and their intracellular signal transduction.
March 30, 2020
Nomura et al. Neuron 2020
Now how can we reduce salt intake without losing that delicious taste based on this?
Dr. Shogo Soma joined the lab
July 1, 2019
Dr. Nomura and Mr. Murakami joined the lab
April 1, 2019
We report the localization of CALHM channels in taste cells
We report the protocol for AAV-Mediated Gene Delivery into Taste Cells
Taruno & Kashio. Methods Mol Biol 2019
We report innate and acquired tolerance to bitter stimuli in mice
Mura#, Taruno# et al. PLOS ONE
Taruno Lab started!
September 1, 2018
We report that CALHM1/CALHM3 is the bona fide neurotransmitter-release channel in type II taste cells
Ma#, Taruno# et al. Neuron 2018
Review article on ATP release channels
Taruno. Int J Mol Sci 2018